Journal of Guangxi Normal University(Natural Science Edition) ›› 2022, Vol. 40 ›› Issue (5): 253-270.doi: 10.16088/j.issn.1001-6600.2021123006

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Review on Rosinane Diterpenes in Pesticide and Pharmaceutical Research

LUO Jiazi1,2,3,4, SONG Xixi1,2,3,4, LI Meishan1,2,3,4, WANG Hengshan1,2,3,4*   

  1. 1. School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
    2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Guilin Guangxi 541004, China;
    3. Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Ministry of Education of China, Guilin Guangxi 541004;
    4. Collaborative Innovation Center for Guangxi Ethnic Medicine (Guangxi Normal University), Guilin Guangxi 541004, China
  • Received:2021-12-30 Revised:2022-04-01 Online:2022-09-25 Published:2022-10-18

Abstract: Rosinane diterpenoids are a class of compounds with a tricyclic diterpene structure, which are widely presented in plants and microorganisms and have a wide range of uses. Due to the in-depth research of natural products and the continuous modification of their structure by organic synthesis, rosinane-type diterpene-type compounds show better bioavailability. This article reviews the application of rosinane-type diterpenes in pesticide and pharmaceutical research from five aspects: pesticide science, pharmacy, chiral drug detection, and research on the relationship between the structure and properties of active compounds.

Key words: rosinane diterpene, pesticides, pesticide co-formulants, pharmacy, pharmaceutic preparation, chiral drug detection, structure-activity relationship

CLC Number: 

  • O629
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