|
Epidemiology and Gene Analysis of HIV-1 in Guangxi,China
KONG Yan-lin, ZHANG Shuai, WANG Xue-wen, LI He-wei, HU Ting-ting, JIANG Qian, JIANG Jiu-xi, PAN Ding-quan, ZHANG Zhen-kai, LI Lin, SUN Chang-rong, LI Jing-yun, LIANG Hao, LIANG Bing-yu
Journal of Guangxi Normal University(Natural Science Edition). 2015, 33 (1):
127-133.
DOI: 10.16088/j.issn.1001-6600.2015.01.021
To determine the epidemiological situation of confirmed HIV-1 infections in Guangxi after 2008,and to understand the distribution of HIV-1 subtypes of Guangxi. An epidemiological survey was made on the HIV-1 infections confirmed after 2008. Among them, 100 come from Guilin, 102 from Laibin, and 103 from Qinzhou. HIV-1 RNA was extracted from their whole blood and amplified by RT-PCR. HIV-1 gag gene was sequenced directly from the PCR product.The results show that there are more men than women in the chosen patients, male to female ratio was 1.99:1.Patients aged ≥20 and ≤49 years old accounted for 56.72% in total, and patients aged 50 years old or older accounted for 44.62%. Farmers accounted for 50.82%.Patients with education level of junior school or below accounted for 76.39%. The patients′s proportion who were transmitted through heterosexual contact is 95.74%. 155 specimens are gained in 305 specimens(amplification rate of 50.82%), then sequence analysis showed that there were 4 HIV-1 subtypes, CRF01-AE(124 samples),B(5 samples),CRF-07BC(12 sample) and CRF-08BC(14 sample).
References |
Related Articles |
Metrics
|