Aiming at the present distinctive internal structure of new-style cinema, a new cellular automaton model is proposed to simulate pedestrian evacuation by introducing “position safety degree”, which identifies the strategy of routing choice. The influences of different internal layouts and different exit positions on evacuation efficiency are investigated via numerical simulation. Furthermore, the typical evacuation scenes are also discussed in detail. The simulation results show that setting up more aisles, especially towards exits will improve the evacuation efficiency greatly. For a cinema with two exits, the optimal evacuation efficiency can be obtained, when these two exits are designed along the left and the right sides of the cinema, respectively, and displayed as a front and back diagonal distribution. In addition, the escape is much easier for the pedestrians close to aisles than those in the central position.

This paper, using the modified logistic-CA model, simulates and predicts urban morphology evolution of Tianjin Binhai New Zone from 1998 to 2030,as well as investigates the Process-pattern-Mechanism under the exogenous scenario, so as to better grasp urban form evolution regularities and enrich the basic theory. It also provides scientific proposal for urban planning and construction layout. The results show that the improved model has good adaptability. The simulation results indicate that from 2014 to 2030, the city will expand around the five clusters, then urban form achieves the connection of north-south urban development belt and Hai River development axis in the form of block filling. It can be concluded that the formevolution of coastal city will undergo four stages, namely core growth, clusters expansion, belt and axis expansion, regional filling. During the process of evolution, the city gradually gets rid of the extermal in fluence and achievse independent self-development. Under the exogenous scenarios, urban form tends to be decentralized, and change alternatively from leaping expansion to filling extension.

In order to solve the problem of flight conflict detection and resolution (CDR) on fixed airway, a CDR method based on allocation of flight levels is proposed, and a distributed multi-agent system is designed for the algorithm implementation. Firstly, a fixed airway net graph is established to model control sector. Secondly, the major factors of the allocation of flight levels are analyzed, and then a priority evaluation model is established. Finally, a multi-agent system based on contract net protocol is designed, which establishes a distributed CDR mode based on independent communication, negotiation and coordination between intersection agents and aircraft agents, rather than an actual centralized mode relying on air traffic controllers. Simulation results show that the flight level distribution method is feasible, and it is closer to actual situation, compared with traditional method based on heading or velocity adjustment. And the designed distributed multi-agent system algorithm can search the optimal solution rapidly, which provides a new solution to the CDR problem.

In order to overcome the deficiency of slow focusing speed of the clarity evaluation function, a fast auto focusing algorithm is proposed based on image processing. Under the condition of changing the object distance conditions only, the function expression of the target defocus by blur difference is derived according to the defocus model of optical imaging system. The expression of defocusing amount is mediated on the Z axis motor to achieve fast focusing. The experimental results show that the ectual target defocusing amount can be precisely estimated to achieve focusing quickly with two images of different degree of defocusing image.

According to the application requirements of greenhouse environment, a set of monitoring system of greenhouse environment factors is developed based on ZigBee wireless network. The monitoring of temperature and humidity, CO₂ concentration is achieved through the wireless network. The whole system consists of field data acquisition controller and remote monitoring software, and the operation of the whole system is simple and wiring is convenient. Field data collector is responsible for the collection of data information and the integration control of the equipment, remote monitoring software is responsible for data analysis, records and figurization. Experiments show that the system base on ZigBee technology has great potential in real-time monitoring of greenhouse environment factors, due to low cost, low power consumption and large capacity of the network.

Heart sound signal reflects the mechanical condition of the heart and cardiovascular system, which is an important signal of the physiological and pathological information about various parts of the human heart. At present, the diagnosis of disease through the heart sound signal method is mainly by manual auscultation. It would be very important to the clinical research of heart disease if can come up with an effective algorithm which can automatically recognize and classify the collected heart sound, judge and even prompt a warning signal when heart sound related to lesions is found. Based on the above described facts, it studied the heart sound by the following aspects: use HKY-06B heart sound sensor to collect heart sound signal; transforming format and storing heart sound signal by the recording software of CoolEditPro2.1, pre-processing, extracting the features of the heart sound signals by means of Mel Frequency. After preprocessing, extracting features, GMM is set. the sampled signals are put into the GMM model to identify whether the sounds are normal sounds or pathological ones.

Several special artificial reverberation models which contain hall reverb, spring reverb, gate reverb, plate reverb are designed. From the point of zero pole figure, impulse response, and frequency response, the reverberation time and echo density of various reverberation models are analyzed and studied. The results show that these special reverberation models with non-cdoration phenomenon have the higher echo density than comb filter and all pass filter reverberation models. Meanwhile,these models have the advantages of adjustable reverberation sound and ideal naturalness, and have a important practical value with can be applied to engineering practice.

The shoreline is one of the most important land resources and its unreasonable utilization could lead to severe pollution and ecological damage.Based on the remote sensing images of different periods, the spatial distribution characteristics and the attribute information of Guangxi shoreline are identified and extracted, according to the waterline, adjacent type of the land cover and land use, texture characteristics and so on. After analyzing spatial distribution, reclamation and attribution of shoreline, the driving force of shoreline change is studied. In the end, the conclusions are achieved: the length of shoreline increases about 102.86 kilometers in thirteen years, and the period of major shoreline changes occurs between 2005 and 2010; The natural shoreline is becoming shorter and shorter, on the contrary, the manual shoreline is getting longer and longer. On the whole, the building of harbour, wharf and the industrical zone are the main causes of the reclamation. The area of reclamation in recent 13 years is about 66.74 kilometers. The growth pole of reclamation lies in Qin-nan District of Qinzhou city, and Gangkou District of Fangcheng city. The shoreline type is rich in natural resources. The biological shoreline and the muddy shoreline are the main types among the natural shoreline, and the cultivtion shoreline is the most outstanding type of the manual shoreline. The results of the research will have great significance in the development of the shoreline resources, protection of the biological environment and the reasonable distriboution of the karbour.

The research on the group inverse and Drazin inverse of the anti-triangular block matrix M=PQI0 was always done under some conditions for the sub-matrices. In this paper, some results are obtained under some new conditions, namely, when P is nonsingular or ind(Q)≤1, sufficient and necessary conditions for the existence of the group inverse of M are developed and the expressions of the group inverse of M are presented. Moreover, based on the above results, the representations for Drazin inverses of M are obtained under conditions ind(P)≤1, P^πQP=0 and ind(P^#QPP^#)≤1, or on the conditions PQQ^π=0 and Q²Q^D+Q^πPQ^π are nonsingular.

A new upper bound on the spectral radius for the Hadamard product of two nonnegative matrices A and B and a new lower bound on the minimum eigenvalue for the Fan product of two M-matrices A and B are given. The estimating formulas of the bounds only depend on the entries of the matrices. Therefore, they are easy to calculate. Numerical examples show that the new formulas can improve some existing ones in some cases.

In this paper, the global attractivity of the max-type difference equation with index x_n=max${\frac{1}{x_{n-k}^{\alpha}},\frac{A_n}{x^{\beta}_{n-k-2}}}$,n=0,1,…, where k∈N and k≥1, 0<α≤1,0<β<1, A_n∈(0,1], x_-k-2,x_-k-1,…,x_-1∈(0,+∞) is studied. Every positive solution of this difference equation is proved to converge to 1.

In this paper, based on the local gird size function, a kind of linear weighted function with piecewise smoothness is constructed. A weighted norm estimate based on finite volume method for two-point boundary value problem is obtained. Furthermore, the exact values of error constants are given and more precise error results are obtained, which provides a theoretical basis for error analysis near a singular point.

The valuation on European lookback option with floating strike price is considered under the Hull-White stochastic volatility model. Using the Taylor series expansion technique, the approximated explicit formulas for the price and delta value of the European lookback option are obtained. Numerical experiments show that the proposed explicit formula performs accurately and efficiently compared with Monte Carlo simulation, and is easy to implement in practice. Finally, the impacts of the key parameters in the volatility process on both the option price and its delta value are analyzed through numerical examples.

A fluorescence polarization technique was established to screen Hsp90 inhibitors and was selected as candidate for further anti-proliferation study. Thermal shift assay was used to confirm the binding effect of cynaroside and Hsp90. Then it was found that cynaroside showed potent and selective antiproliferation activities against non-small lung cancer cells among 14 strains of cancer cells. The colonial assay, western blot and flow cytometry were employed to investigate its possible mechanism. The results showed that cynaroside could inhibit the proliferation of non-small lung cancer cells in a dose-dependent manner and induce the degradation of Raf-1, and HER2 expression. Moreover, cynaroside induced G2/M arrest in H460 cell and triggered apoptosis by up-regulatiing Bax expression. Finally, the results displayed that cynaroside, one of the flavonoids, formed antineoplastic activity by inhibiting Hsp90 activity to degrade its client proteins in H460 cells, inducing G2/M phase arrest and triggering apoptosis by up-regulating Bax expression.

Meconopsis horridula Hook.f. & Thomson was chosen as raw materials to study the optimum parameters of SCF-CO₂ extraction of Meconopsis horridula Hook.f. & Thomson and chemical constituents of extractive matters. SCF-CO₂ extraction condition was selected by uniform design. In the experiment, three factors should be taken into consideration, such us the extraction time, extraction pressure and extraction temperature. GC-MS was applied to analyze the extraction. The optimum condition were obtained: the extraction time was 180 minutes,the extraction pressure was 28 MPa and the extraction temperature was 45 ℃. 55 compounds in Meconopsis horridula Hook.f. & Thomson were detected by GC-MS and 53 compounds were identified by MS combined with Kovats retention index. The major constituents of the extractive matters were clionasterol, linoleic acid and palmic acid.

In boric acid-borax buffer solution medium, with the help of Co²⁺, and the CTMAB surfactant as a sensitizer, the benzoic acid was sensitized to emit strong fluorescence. Based on this, a new method for the determination of benzoic acid was established. To optimize the experimental conditions, at c_Co²⁺=3×10^-3 mol/L, c_CTMAB=7×10^-4 mol/L, pH=8.4, T=30 ℃, water bath heating 22 min, 302 nm as the maximum excitation wavelength, 608 nm as the maximum emission wavelength, determination of benzoic acid was performed. The linear range is 5×10^-6~1.0×10^-3 g/L and the detection limit for 2×10^-6 g/L. The recovery rate is 101%～105% for the determination of benzoic acid.

In hydrochloric acid medium containing boric acid, Mo(VI) catalyzed bromate oxidation of iodine ion to form iodine, and then it reacted with polyvinyl alcohol to form blue green complex. It exhibited a maximum absorption peak at 670 nm, and a maximum resonance scattering peak at 369nm. In the selected conditions, there was a good linear relationship between the absorbance and resonance Rayleigh scattering intensity and the concentration of a certain range of bromate. Therefore, two new methods of determination of bromate were put forward in drinking water with spectrophotometry and resonance Rayleigh scattering. By using the spectrophotometric method, the regression equation was ΔA= 0.086ρ_BrO^-3-0.013, the linear range was from 1 to 30 μg/L, with a detection limit of 0.5 μg/L. By using the resonance Rayleigh scattering method, the regression equation was ΔI=406.44ρ_BrO^-3+36.36, the linear range was from 0.1 to 2 μg/L, with a detection limit of 0.05 μg/L. Bromate in drinking water was determined by using resonance Rayleigh scattering method with satisfactory results.

35 infrared cameras were set in 15 hm² Forest Dynamics Plot of Nonggang National Nature Reserve from August 2012 to October 2013 in order to monitor diversity of mammals and birds. Based on the pictures of Muntiacus muntjak captured by infrared cameras, the activity pattern of Muntiacus muntjak was analyzed using three activity indices, namely daily-discrepancy index α, diurnal-nocturnal index β, seasonal-activity index γ. The results showed that diurnal activity pattern showed significant difference, with two peak at 6:00-10:00 and 16:00-20:00. Although there was marked variation in monthly β values, the mean β value was 0.58 (>13/24), indicating that Muntiacus muntjak is a twilight diurnal animal. There was marked variation in monthly α values. Compared with dry season, the α values were higher in the rainy season. No significant variations were found in the γ values between seasons and years. But the time of activity peak differed between seasons and years. These variations may be related to seasonal variation in temperature and food availability of limestone habitats.

To investigate effect of low temperature Stress on cell morphology of liver, spleen and gill in Egyptian strains of Nile tilapia, 135 tilapias were selected to study the effects of different cold stress on blood physiological and biochemical changes using artificial indoor cooling and electron microscopy. The average body weight of the tilapia were (150±2) g which were randomly divided into 25 ℃, 15 ℃ and 12 ℃ 3 groups with three repeats, 15 tilapias for each repeat. The results showed that tilapia went into at 15 ℃ 16 d, at 12 ℃ of 72 h tilapia were in a coma and death. The damage degree of liver, spleen and gill cells of tilapia were enhanced with water temperature reduced, at 12 ℃, the most serious occurred. when the temperature was 15 ℃, the edge of the liver cells was not clear and formed the small crushed, the edge of the spleen appeared minor dissolved, part of the gill lamellae was fractured and capillary mild hyperemia; when temperature was 12 ℃, the number of mitochondria in liver cells decreased with serious structural fragmentation. Endoplasmic reticulum structure was at a state of fragmentation and the edge of the spleen tissue began to dissolve. Similar changes appeared in spleen cells and liver cells gill lamellae faratured and capillary congested seriously.

An investigation of ants in Jinzhongshan Nature Reserve was made, and the ant fauna was analyzed. 89 species belonging to 46 genera, 9 subfamilies were recognized, among them 1 species is a new species, 4 species are new records to Guangxi. Analysis of species components suggest that Myrmicinae and Formicinaeisthe were dominant groups, forming the majority of the ant fauna in the reserve. At the level of world animal geographical divisions, fauna analysis showed that oriental species and oriental-palaearctic species were primary part in Jinzhongshan Nature Reserve, with typical oriental feature and close to palaearctic fauna. At the level of Chinese animal geographical divisions, ant fauna of Jinzhongshan Nature Reserve was closest to that of Central China, the relationships between other divisions become farther with increasing of distance.

The content of Leptin (LEP) and homocysteine (HCY) of cardiovascular diseases (CVD) markers in HIV infected patients was detected in Highly active antiretroviral therapy (HAART) process and the effect on prevention of CVD in HIV infected patients was determined to provide a basis for early prevention in HIV infection complicated with CVD. Methods: Serum samples obtained from 30 healthy subjects and 62 HIV infected patients(28 treatment nalve and 34 treatment experienced patients) were analyzed by enzyme-linked immunosorbent assay (ELISA) to determine the HCY and LEP contents.The Results show that the level of serum HCY in HIV infected treatment group was obviously higher than that of untreated group and normal control group (P<0.01).There was no marked difference of the LEP level between the three controls(P>0.05). Serum HCY and CD4⁺T lymphocyte count, treatment time and TG were positively correlated (P<0.01). Dynamically detecting the level of HCY and LEP may be beneficial to the early prevention of HIV infection complicated with CVD.

To explore the correlation of lower-limb muscle of patients with different characteristics of the cerebral palsy, and analyze of the differences and the similarity in the patients with the different characteristics, which provide references for clinical research and treatment of children with cerebral palsy and rehabilitation. Twenty-two(2-12 years,18 males and 4 females; age 5.8±2.0 years) children with CP who came to the physical therapy rehabilitation center volunteered to participate in the experiment in Shenzhen Disabled Rehabilitation Center, Guangdong, China. The study was approved by the institutional review board of Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences. According to the experienced rehabilitation therapist’s clinical evaluations, among all the participants were divided into three groups, including 8 diagnosed to be cerebral palsy with spastic characteristic, and 9 diagnosed with hemiplegia, and 5 diagnosed with other features. There was no significant difference in the gender, age, mental, social and adaptive behavior, Gross motor function measure and balance of the three groups was no significant difference (P>0.05).The patients straight for 5 meters at their self-selected comfortable speed toward a target line on the floor,and were assessed on daily living function with the muscular tension of triceps and the subscale of Berg.Surface electromyography (EMG) from GM and TA were recorded and MP150 system(BioNomadix 2-Channel EMG system, BIOPAC Systems, Inc, Goleta, USA) was used to collect the data. SPSS Statistics, version 19.0 were used to analyze the statistics. Results and conclusion: There was great difference among the children with different characteristics. Spasticity and other features affected the relationship of lower-limb muscle of patients with cerebral palsy and improved the muscular tension of triceps, and the correlation of lower-limb muscle of children with hemiplegia was significant, which provided useful information to treat the children with different characteristics of cerebra palsy with different methods.

In order to know the soil aggregate characteristic on artificial forest soils with different sieve strength, four artificial forest soils with 1.5 mm and 2.5 mm sieve strength (Phyllostachys edulis forest, Cunninghamia lanceolata forest, Eucalptus grandis×E. urophylla forest and Pinus massoniana forest) were selected for study by means of AS200 in Northeast Guangxi. Soil aggregate were obtained with dry sieving method and MWD for soil stability analysis. The result shows that there are no significant difference between Cunninghamia lanceolata forest and Eucalptus grandis×E.urophylla, but both significantly greater than Phyllostachys edulis forest and Pinus massoniana forest. The particle content ranging from 0.5-1 mm to 0.25-0.5 mm and <0.25 mm with Eucalptus grandis×E. urophylla forest growing negatively while Phyllostachys edulis forest and Cunninghamia lanceolata forest growing positively. The content of SOC (Cunninghamia lanceolata forest, Eucalptus grandis×E. urophylla forest and Pinus massoniana forest) increased while soil aggregate decreased.From the point of view of soil aggregate, it benefits the stability of Phyllostachys edulis forest soil, while go against soil stability of Pinus massoniana forest. There are significant differences among four artificial forest soils, and it was directly affected by the different sieve strength in Karst soil.