Journal of Guangxi Normal University(Natural Science Edition) ›› 2015, Vol. 33 ›› Issue (3): 98-103.doi: 10.16088/j.issn.1001-6600.2015.03.015

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Composition of Meconopsis horridula Hook.f. & Thomson in SCF-CO2 Extraction

ZENG Qing-yi1,2,3, LIU Xiao-cui1,2,3, BAI Xue1,2,3, LIN Peng-cheng1,2,3, JI Shou-xiang1,2   

  1. 1. College of Pharmacy,Qinghai University for Nationalities,Xining Qinghai 810007, China;
    2. Key Laboratory of PlantResources of Qinghai-Tibet Plateau in Chemical Research, Qinghai University for Nationalities, Xining Qinghai 810007,China;
    3. Key Laboratory of Pharmaceutical Analysis in Qinghai Province, Xining Qinghai 810007, China
  • Received:2015-03-18 Online:2015-05-10 Published:2018-09-20

Abstract: Meconopsis horridula Hook.f. & Thomson was chosen as raw materials to study the optimum parameters of SCF-CO2 extraction of Meconopsis horridula Hook.f. & Thomson and chemical constituents of extractive matters. SCF-CO2 extraction condition was selected by uniform design. In the experiment, three factors should be taken into consideration, such us the extraction time, extraction pressure and extraction temperature. GC-MS was applied to analyze the extraction. The optimum condition were obtained: the extraction time was 180 minutes,the extraction pressure was 28 MPa and the extraction temperature was 45 ℃. 55 compounds in Meconopsis horridula Hook.f. & Thomson were detected by GC-MS and 53 compounds were identified by MS combined with Kovats retention index. The major constituents of the extractive matters were clionasterol, linoleic acid and palmic acid.

Key words: Meconopsis horridula Hook.f. &, Thomson, SCF-CO2, uniform design, GC-MS, Kovats

CLC Number: 

  • O415.3
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