赤苍藤化学成分及其抗炎活性研究

doi:10.16088/j.issn.1001-6600.2024082002

Abstract

Abstract: Erythropalum scandens Blume is a leafy vegetable and emerging medicinal plant widely distributed in Guangxi, China. However, the product development of the title plant is limited due to the insufficient investigations on its secondary metabolites. To uncover the bioactive components of E. scandens, herein, the results of a systematic phytochemical investigation on E. scandens were reported, which were the isolation and structural characterization of 11 compounds belonging to different structural types. All the compounds were reported from the genus Erythropalum for the first time. Moreover, all the isolated compounds showed moderate to good anti-inflammatory activity against LPS-stimulated RAW264.7 cells, with acetanilide being the most potent example, which possessed better potency compared with the clinical anti-inflammatory drug indomethacin.

Key words: Erythropalum scandens Bl., Erythropalum Bl., chemical composition, anti-inflammatory activity

CLC Number: R284.1

GAO Defeng, SHI Zhimian, DOU Boqiang, WEI Haiye, LI Yuyan, HUANG Yan, SU Juncheng. Chemical Constituents and Anti-inflammatory Activities of Erythropalum scandens Bl.[J].Journal of Guangxi Normal University(Natural Science Edition), 2025, 43(2): 258-264.

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Chemical Constituents and Anti-inflammatory Activities of Erythropalum scandens Bl.

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