Journal of Guangxi Normal University(Natural Science Edition) ›› 2015, Vol. 33 ›› Issue (4): 103-107.doi: 10.16088/j.issn.1001-6600.2015.04.017

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Synthesis and Antibacterial Activity of Ternary Zinc Complex

LIU Han-fu1,2, MA Xian-li1, CHEN Su-yi 1, SHEN Xue-song1, HUANG Fu-ping2   

  1. 1.College of Pharmacy, Guilin Medical University, Guilin Guangxi 541004, China;
    2. College of Chemistry and Pharmaceutical Science,Guangxi Normal University, Guilin Guangxi 541004, China
  • Received:2015-07-20 Online:2015-12-25 Published:2018-09-21

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Abstract: A new complex [Zn2(C12H8N5)2(C4H2O4)(H2O)2]n was synthesized with fumaric acid and 3,5-bis(3-pyridyl)-1,2,4-triazole by hydro-thermal method. The results of single-crystal X-ray diffraction analysis show that the title complex crystallizes in the Monoclinic space group P21/n with a=1.259 1(3) nm, b=0.776 10(16) nm, c=1.450 1(3) nm, β=94.00(3) °, Z=4. In the title complex, the central ion Zn(II) was coordinated by two O atoms and two N atoms, which consist of one O atom of fumaric acid and another O atom of H2O, two N atoms of two 3,5-bis(3-pyridyl)-1,2,4-triazole. So, Zn(II) and the four coordination atoms form distorted tetrahedral geometry. The antibacterial activity was tested in vitro. The result show that, title complex and its ligand have some antibacterial activity for three kinds of bacteria.

Key words: fumaric acid, 3,5-bis(3-pyridyl)-1,2,4-triazole, crystal structure, complex, antibacterial activity

CLC Number: 

  • O641
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