Journal of Guangxi Normal University(Natural Science Edition) ›› 2023, Vol. 41 ›› Issue (1): 24-37.doi: 10.16088/j.issn.1001-6600.2022011605

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Research Progress on Chemical Components and Pharmacological Effects of Zanthoxylum nitidum (Roxb.) DC. in Recent Five Years

CHEN Yao1,2,3,4, LI Meishan1,2,3,4, QIN Feng1,2,3,4, WANG Hengshan1,2,3,4*   

  1. 1. School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
    2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Guilin Guangxi 541004, China;
    3. Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Ministry of Education, Guilin Guangxi 541004, China;
    4. Collaborative Innovation Center for Guangxi Ethnic Medicine (Guangxi Normal University),Guilin Guangxi 541004, China
  • Received:2022-01-16 Revised:2022-03-25 Online:2023-01-25 Published:2023-03-07

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Abstract: Zanthoxylum nitidum (Roxb.) DC., a kind of Zanthoxylum plant of Rutaceae family, is mainly distributed in Guangxi, Fujian, Guangdong and Yunnan provinces in China. The root, stem, leaf and peel ofZ. nitidum can be used for medicine, which has the effects of promote blood circulation to remove blood stasis, promote qi circulation to relieve pain, disperse wind to dredge collaterals and remove toxicity to achieve detumescence. It is one of the national medicines with Guangxi characteristics, and is the classic Laoban medicine of Yao people “Ru Shan Hu” and Zhuang medicine “Liang Bei Zhen”. At present, the chemical components isolated from Z. nitidum, including alkaloids, coumarins, lignans, flavonoids and other compounds, which possess anti-inflammatory, analgesic, hemostatic, antitumor, antibacterial and other pharmacological effects. The chemical constituents and pharmacological activities of Z. nitidum at home and abroad in recent five years are reviewed based on literatures search in this paper, which will provide references for further research and development of the medicinal values of this plant.

Key words: Zanthoxylum nitidum (Roxb.) DC., alkaloid, coumarin, anti-inflammatory, antibacterial, anticancer

CLC Number: 

  • R284
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