Journal of Guangxi Normal University(Natural Science Edition) ›› 2012, Vol. 30 ›› Issue (2): 71-77.

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Synthesis of Indanones Derivatives

PAN Cheng-xue1, JIANG Xiang-liu2, ZHANG Hong-bin2   

  1. 1.State Key Laboratory Cultivation Base for the Chemistry andMolecular Engineering of Medicinal Resources, College of Chemistry and Chemical Engineering,Guangxi Normal University,Guilin Guangxi 541004,China;
    2.Key Laboratory of Medicinal Chemistry for Natural Resource,Ministry of Education,College of Chemistry and Chemical Engineering,Yunnan University,Kunming Yunnan 650091,China
  • Received:2011-12-03 Online:2012-06-20 Published:2018-12-03

Abstract: Eight indanones derivatives were synthesized by threeprocedures for preparation of indanone derivatives starting from aromatic aldehydes or 1,2-dimethoxy-benzene with the Friedel-Crafts acylation,Nazarov cyclization or Pinacol rearrangement as the key stepsin the synthesis,and the productswere characterized and confirmed by 1H NMR and 13C NMR.The protocols possess the advantages of cheap material,simple operation and high yields.

Key words: indanone derivatives, Nazarov cyclization, Pinacol rearrangement, synthesis

CLC Number: 

  • O625
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