广西师范大学学报（自然科学版） ›› 2022, Vol. 40 ›› Issue (5): 253-270.doi: 10.16088/j.issn.1001-6600.2021123006

• 综述 • 上一篇    下一篇

松香烷型二萜在农药及药学中的研究进展

罗家锱1,2,3,4, 宋习习1,2,3,4, 李梅珊1,2,3,4, 王恒山1,2,3,4*   

  1. 1.广西师范大学 化学与药学学院, 广西 桂林 541004;
    2.省部共建药用资源化学与药物分子工程国家重点实验室(广西师范大学), 广西 桂林 541004;
    3.药用资源化学与药物分子工程教育部重点实验室(广西师范大学),广西 桂林 541004;
    4.广西民族药省部共建协同创新中心 (广西师范大学), 广西 桂林 541004
  • 收稿日期:2021-12-30 修回日期:2022-04-01 出版日期:2022-09-25 发布日期:2022-10-18
  • 通讯作者: 王恒山(1965—), 男, 浙江温州人, 广西师范大学教授, 博导。E-mail: whengshan@163.com
  • 基金资助:
    国家自然科学基金(21977021, 81760626, 22111530012); 广西自然科学基金(AB17292075)

Review on Rosinane Diterpenes in Pesticide and Pharmaceutical Research

LUO Jiazi1,2,3,4, SONG Xixi1,2,3,4, LI Meishan1,2,3,4, WANG Hengshan1,2,3,4*   

  1. 1. School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
    2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Guilin Guangxi 541004, China;
    3. Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University), Ministry of Education of China, Guilin Guangxi 541004;
    4. Collaborative Innovation Center for Guangxi Ethnic Medicine (Guangxi Normal University), Guilin Guangxi 541004, China
  • Received:2021-12-30 Revised:2022-04-01 Online:2022-09-25 Published:2022-10-18

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摘要： 松香烷型二萜是具有三环二萜结构的一类化合物,广泛存在于植物、微生物体内,具有广泛的用途,显示出较好的生物利用度。本文从农药科学、药学、药剂学、手性药物检测、活性化合物结构与性质关系5个方面综述松香烷型二萜在农药及药学研究中的应用。

关键词: 松香烷型二萜, 农药, 农药助剂, 药学, 药物制剂, 手性药物检测, 构效关系

Abstract: Rosinane diterpenoids are a class of compounds with a tricyclic diterpene structure, which are widely presented in plants and microorganisms and have a wide range of uses. Due to the in-depth research of natural products and the continuous modification of their structure by organic synthesis, rosinane-type diterpene-type compounds show better bioavailability. This article reviews the application of rosinane-type diterpenes in pesticide and pharmaceutical research from five aspects: pesticide science, pharmacy, chiral drug detection, and research on the relationship between the structure and properties of active compounds.

Key words: rosinane diterpene, pesticides, pesticide co-formulants, pharmacy, pharmaceutic preparation, chiral drug detection, structure-activity relationship

中图分类号: 

  • O629
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