Journal of Guangxi Normal University(Natural Science Edition) ›› 2021, Vol. 39 ›› Issue (2): 139-143.doi: 10.16088/j.issn.1001-6600.2020060902

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Secondary Metabolites of Endophytic Fungus GDG-178 from Sophora tonkinensis

LI Benchao1,2, LIANG Yan1,2, QIN Xiaoya1,2, MO Tuxiang1,2, XU Zhaolong1,2, LI Jun1,2, YANG Ruiyun1,2*   

  1. 1. College of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
    2. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine Guangxi Normal University, Guilin Guangxi 541004, China
  • Received:2020-06-09 Revised:2020-09-10 Online:2021-03-25 Published:2021-04-15

Abstract: Ten compounds were isolated from the metabolites of endophytic fungus GDG-178(Fusarium equiseti)by using silica gel column chromatography, ODS chromatography, SephadexLH-20 and semi-prepared HPLC. The structures of these compounds, beauvericin (1), fusaproliferin (2), 11-epiterpestacin (3), 3-indoleacetic acid (4), indole-3-methylethanoate (5), 4-methyl-5,6-dihydro-2H-pyran-2-one (6), sterigmatocystin (7), 2′-hydroxydecanylpentadec-5,8,10,12-tetraneoate (8), 19-norergosta-5,7,9,22-tetraene-3β-ol (9) and p-hydroxy benzaldehyde (10), were identified by spectral analysis. Compounds 7-10 were obtained from Fusarium sp. for the first time. And compounds 5 and 6 were firstly obtained from Fusarium equiseti.

Key words: Sophora tonkinensis, endophytic fungi, Fusarium sp., Fusarium equiseti, metabolites

CLC Number: 

  • O629.9
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