Journal of Guangxi Normal University(Natural Science Edition) ›› 2016, Vol. 34 ›› Issue (4): 55-59.doi: 10.16088/j.issn.1001-6600.2016.04.009

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Antioxidant and Antitumor Activities of Extracts from Taxus chinensis var. mairei

LIU Xi1, ZHANG Ye2   

  1. 1. College of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
    2. Department of Chemistry and Pharmaceutical Science, Guilin Normal College, Guilin Guangxi 541001, China
  • Received:2016-04-28 Online:2016-07-18 Published:2018-07-18

Abstract: Under ultrasound, Taxus chinensis var. mairei were extracted with ethanol at 80 ℃ to offer ethanol extract (EE). EE was further extracted with chloroform and separated by column chromatography to offer taxol. Their antioxidant and antitumor activities were then evaluated. The antioxidant activity screening results showed that EE exhibited better scavenging activity than the common antioxidant BHT in these four assays, with IC50 of 13.19±1.50, 2.65±0.35, 25.33±1.75 and 343.00±2.13 mg/L, respectively, while taxol showed the worst, indicating excellent antioxidant activity of EE. The antitumor activity screening results demonstrated that taxol showed better inhibition than EE, with IC50 of 3.45±1.37, 6.20±0.88, 1.98±0.49 and 1.15±0.27 mg/L, respectively.

Key words: Taxus chinensis var. mairei, taxol, antioxidant activity, antitumor activity, ultrasound-assisted extract

CLC Number: 

  • R282
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