Journal of Guangxi Normal University(Natural Science Edition) ›› 2021, Vol. 39 ›› Issue (6): 13-23.doi: 10.16088/j.issn.1001-6600.2021022801

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Research Progress on Carotenoid Biosynthesis and Metabolic Regulation in Microalgae

PANG Bingbing1,2,3, YE Fengcai1,2,3, LI Yuyan1,2,3, SHANG Changhua1,2,3*   

  1. 1. Guangzhou Institute of Energy Conversion, Key Laboratory of Renewable Energy, Chinese Academy of Sciences, Guangdong Key Laboratory of New and Renewable Energy Research and Development, Guangzhou Guangdong 510640, China;
    2. College of Life Sciences, Guangxi Normal University, Guilin Guangxi 541006, China;
    3. Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin Guangxi 541006, China
  • Received:2021-02-28 Revised:2021-05-01 Online:2021-11-25 Published:2021-12-08

Abstract: Energy consumption and environmental pollution made biodiesel production from microalgae a hot spot. Comprehensive utilization of microalgae by simultaneously extracting carotenoid and oil, can effectively reduce the production cost of microalgae biodiesel. Although carotenoids are important active substances, little has been known about carotenoid biosynthesis and its metabolic regulation in microalgae so far. In order to better understand and manipulate carotenoid metabolism for enhancement of carotenoid production in microalgae, presented an overview of research advances on carotenoid biosynthesis and its metabolic regulation in microalgae were presented, including carotenoid biosynthesis pathway, strategies for improving carotenoid accumulation (biochemical regulation, mutagenesis and genetic engineering strategy). Effects of environmental factors on carotenoid accumulation were illustrated. Two genetic engineering strategies were summarized, including enhancement of expression of key enzyme genes in carotenoid biosynthesis pathway, enhancement of expression of transcription factor genes related to regulation of carotenoid biosynthesis pathway. The prospect of research on carotenoid metabolism was also discussed in microalgae.

Key words: microalgae, carotenoid, metabolic regulation, genetic engineering

CLC Number: 

  • Q943.2
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