Journal of Guangxi Normal University(Natural Science Edition) ›› 2017, Vol. 35 ›› Issue (1): 62-68.doi: 10.16088/j.issn.1001-6600.2017.01.011

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Response Surface Optimization of Flavonoids Extraction from Nepeta coerulescens

YE Ju1,2, SUN Liqing1,3, JI Shouxiang1   

  1. 1. Key Laboratory of Pharmaceutical Analysis in Qinghai Province, Qinghai University for Nationalities, Xining Qinghai 810007, China;
    2. Qinghai-Tibet Plateau Plant Chemical Key Laboratory, Qinghai University for Nationalities, Xining Qinghai 810007, China;
    3. College of Chemistry and Chemical Engineering, Qinghai University for Nationalities, Xining Qinghai 810007, China
  • Online:2017-01-20 Published:2018-07-17

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Abstract: Nepeta coerulescens flavonoids were extracted with ethanol. The effects of time, temperature, the ethanol solution concentration on the content of Nepeta coerulescens were investigated in single-factor test. The preferred extraction conditions were determined by RSM. The optimization extraction conditions by RSM analysis were obtained at ethanol concentration of 35%, temperature of 65 ℃ and time of 70 min. Under the optimization extraction conditions, the extraction ratio of flavonoids can reached 0.351%.

Key words: Nepeta coerulescens, flavonoids, response surface methodology, optimize

CLC Number: 

  • Q946.8
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