短指软珊瑚Sinularia sp.内生真菌Ta31-2代谢产物研究(Ⅱ)

广西师范大学学报（自然科学版） ›› 2014, Vol. 32 ›› Issue (4): 91-95.

短指软珊瑚Sinularia sp.内生真菌Ta31-2代谢产物研究(Ⅱ)

周德雄^1,2, 王歆竹^1,2, 徐伟峰^1,2, 杨瑞云^1,2, 邵长伦³, 李俊⁴

1. 广西师范大学化学与药学学院,广西桂林541004;
2. 广西师范大学药用资源化学与药物分子工程教育部重点实验室,广西桂林541004;
3. 中国海洋大学医药学院,山东青岛266003;
4. 广西师范大学环境与资源学院,广西桂林541004

收稿日期:2014-09-11 发布日期:2018-09-26
通讯作者: 杨瑞云(1978-),女,广西桂林人,广西师范大学研究员,博士。E-mail:yang_rui_yun@163.com
基金资助:
药用资源化学与药物分子工程教育部重点实验室资助项目(CMEMR2012-A21, CMEMR2013-C07, CMEMR2013-A06);广西自然科学基金资助项目(2014GXNSFAA118055);广西医药产业人才小高地资助项目(1310)

Metabolites of Endophytic Fungus Ta31-2 from Soft Coral Sinularia sp. (Ⅱ)

ZHOU De-xiong¹^{, 2}, WANG Xin-zhu¹^{, 2}, XU Wei-feng¹^{, 2}, YANG Rui-yun¹^{, 2}, SHAO Chang-lun³, LI Jun⁴

1. College of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin Guangxi 541004, China;
2. Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Ministry of Education, Guangxi Normal University, Guilin Guangxi 541004, China;
3. College of Medicine and Pharmacy, Ocean University of China, Qingdao Shandong 266003, China;
4. College of Environment and Resources, Guangxi Normal University, Guilin Guangxi 541004, China

Received:2014-09-11 Published:2018-09-26

摘要/Abstract

摘要： 从短指软珊瑚Sinularia sp.内生真菌Ta31-2的代谢产物中分离得到10个化合物,利用波谱技术确定其结构分别为硬脂酸(1)、软脂酸(2)、肉豆蔻酸(3)、癸酸甲酯(4)、麦角甾醇(5)、fusanolide B(6)、丁二酸(7)、curvulalide(8)、modiolide A(9)和neoechinulin A(10)。其中,fusanolide B(6)为首次从海洋真菌中分离得到,curvulalide(8)和 neoechinulin A(10) 为首次从软珊瑚Sinularia sp. 内生真菌中分离得到。

关键词: 软珊瑚Sinularia sp., 内生真菌, 代谢产物

Abstract: Ten compounds, including stearic acid (1), palmitic acid (2), myristic acid (3), methyl decanoate (4), ergosterol (5), fusanolide B (6), succinic acid (7), curvulalide (8), modiolide A (9) and neoechinulin A (10), were isolated from the metabolites of a soft coral Sinularia sp. endophytic fungus Ta31-2. Their structures were elucidated by using spectroscopic methods. Compounds 8 and 10 were isolated from soft coral firstly, and 6 was isolated from marine fungi for the first time.

Key words: Sinularia sp., endophytic fungi, metabolites

中图分类号:

O629.9

周德雄, 王歆竹, 徐伟峰, 杨瑞云, 邵长伦, 李俊. 短指软珊瑚Sinularia sp.内生真菌Ta31-2代谢产物研究(Ⅱ)[J]. 广西师范大学学报（自然科学版）, 2014, 32(4): 91-95.

ZHOU De-xiong, WANG Xin-zhu, XU Wei-feng, YANG Rui-yun, SHAO Chang-lun, LI Jun. Metabolites of Endophytic Fungus Ta31-2 from Soft Coral Sinularia sp. (Ⅱ)[J]. Journal of Guangxi Normal University(Natural Science Edition), 2014, 32(4): 91-95.

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