Abstract: As modern society diversification develops,interdisciplinary studies have turned out to be the inherent need of this irreversible trend.But the problem is that there are thousands of well-developed subjects in the world and the discoveryof possibility to integrate different domains can only be handled by specialists in different domains separately.The reason for this is obviously that no one can master all knowledge in all domains.Therefore,an algorithm should be broughtout to calculate the relevance between two domains.By this method,it can figureout which domain is more relevant with a specified domain,and thus it might be possible to start a cross-domain research or build up a new subject.

Key words: domain knowledge, relevance, Web mining, baidupedia