DNA凝聚理论模拟研究

doi:10.16088/j.issn.1001-6600.2017.03.007

Abstract

Abstract: In order to identify the mechanism of DNA condensation further, a strong correlation model is established based on the strong correlation of condensed counterios and Monte Carlo simulation is employed to study the properties of DNA condensation. During the condensation process, gyration radii of condensed conformation appear step-wise manner indicating the discontinuousness of process of DNA condensation. Autocorrelation of the segment reflects the number of loop structure in the condensed conformation, the condensed phase diagram shows the complexity of the condensed conformation, the majority of condensed conformations take on the complex flower structure, and in comparison with flower structure, the occurrence rate of the toroidal structure is small. All the results mentioned above show strong highlight into the mechanism of DNA condensation.

Key words: condensed balanced ions, strong correlation, DNA condensation, Monte Carlo simulation, gyration radius

CLC Number:

ZHANG Min,GU Lingyun, ZHOU Xun,LIU Yanhui. Simulation Study of DNA Condensation Theory[J].Journal of Guangxi Normal University(Natural Science Edition), 2017, 35(3): 53-62.

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